| Gene Symbol | CREBBP |
| Full Name | CREB Binding Protein |
| Chromosome | 16p13.3 |
| Protein Type | Transcription Factor |
| Function | is a transcriptional coactivator that acetylates histones and transcription factors |
| Primary Expression | most neuronal subtypes including pyramidal cells, interneurons - Glia: Present in astrocytes and [microglia](/entities/mic |
| Molecular Weight | 265 kDa |
| Pathways | NF-κB |
| UniProt ID | Q92793 (CREBBP) |
| NCBI Gene ID | 1387 |
| Ensembl ID | ENSG00000105383 |
| OMIM | 600140 |
| GeneCards | CREBBP |
| Human Protein Atlas | CREBBP |
| HAT domain (KIX domain) | Catalytic core acetylating histones |
| Associated Diseases | ALS, Cancer, Parkinson, Tumor |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACAT1, AMPK, AND, APOPTOSIS, ATG, BCL2 |
| KG Connections | 489 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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