protein 1,277 words KG: ACEPROTEIN
Contents

ACE Protein

🔬 Protein Info
Gene SymbolACE
Full NameAngiotensin Converting Enzyme
AliasesACE1, CD143, DCP1
Chromosome17q23.3
Protein TypeProtease
FunctionConverts angiotensin I to angiotensin II
Molecular Weight149.7 kDa
Amino Acids1306
PathwaysRenin-angiotensin system, Bradykinin metabolism
UniProt IDP12821
NCBI Gene ID1636
Ensembl IDENSG00000159640
OMIM106180
GeneCardsACE
Human Protein AtlasACE
Associated DiseasesAls, Alzheimer, Alzheimer's disease, cancer, Cardiac
InteractionsActin, ALZHEIMER, ALZHEIMER DISEASE, AMYLOID, AND, APOPTOSIS
SciDEX HypothesesMicroglial ACE Enhancement for Amyloid Clearance
KG Connections330 knowledge graph edges
DatabasesGeneCardsHPASTRING

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UniProtWikipedia

Related Hypotheses (13)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.72
Matrix Stiffness Normalization via Targeted Lysyl Oxidase In
Score: 0.71
Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.71
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68
Osmotic Gradient Restoration via Selective AQP1 Enhancement
Score: 0.68
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
APOE-TREM2 Interaction Modulation
Score: 0.74
...
Score: 0.68
Prohibitin-2 Mitochondrial Cross-Seeding Hub Disruption
Score: 0.47
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (7)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (6)

Plasma ATN biomarkers across AD continuum in Chilean cohort
clinical · proposed · Score: 0.95
Intensive Medical Treatment vs Usual Care in Women with ANOC
clinical · proposed · Score: 0.95
ACEs and Motoric Cognitive Risk Syndrome in Chinese Older Ad
clinical · proposed · Score: 0.95
Preinjury ACE-I/ARB exposure and outcomes in transfused trau
clinical · proposed · Score: 0.95
N-of-1 Clinical Trial Design for CBS/PSP
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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