gene 623 words KG: NRXN1
Contents

NRXN1 Gene

🧬 Gene Info
Gene SymbolNRXN1
Full NameNeurexin-1
Chromosome2p16.3
FunctionNRXN1 encodes neurexin-1, a presynaptic cell adhesion molecule that mediates synaptic contact between neurons and is essential for synapse formation and function.
Molecular Weight180 kDa
PathwaysNeuroprotection, Synaptic Plasticity, synaptic plasticity
UniProt IDQ9UHB7
NCBI Gene ID9378
Ensembl IDENSG00000179915
OMIM600565
GeneCardsNRXN1
Human Protein AtlasNRXN1
Synaptic AdhesionBinds to neuroligins (postsynaptic) to form synaptic connections
Presynaptic DifferentiationInduces presynaptic specialization
Synaptic TransmissionRegulates neurotransmitter release
Associated DiseasesAging, Als, Alzheimer, Schizophrenia
InteractionsActin, ALZHEIMER, ALZHEIMER'S DISEASE, AND, APP, BSN
KG Connections96 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (1)

C1q Binding to Specific Synaptic Proteomes via Neurexin/Neur
Score: 0.55

Knowledge Graph (12 edges)

NRXN1 activates BSN
NRXN1 activates GBA
NRXN1 activates CELF4
NRXN1 associated_with CHRNA7
NRXN1 associated_with SNAP29
GRIN2A co_discussed NRXN1
NCAM2 co_discussed NRXN1
NRXN1 co_discussed RORA
RORB activates NRXN1
NRXN1 activates RORB

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