concept

KIAA0247

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KIAA0247: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

36Connections

0Hypotheses

0Analyses

25Outgoing

11Incoming

0Experiments

0Debates

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💡 Concept Info

Name	KIAA0247
Key Genes/Proteins	APOPTOSIS, AUTOPHAGY, CANCER, DNA, DRAGO, GENES
Related Diseases	Aging, Cancer
Related Pathways	Apoptosis, Autophagy

Pathway Diagram

graph TD
    KIAA0247["KIAA0247"]
    KIAA0247 -->|"involved_in"| DNA_Damage_Response["DNA Damage Response"]
    KIAA0247 -->|"interacts"| TP53["TP53"]
    KIAA0247 -->|"activates"| Tumor["Tumor"]
    KIAA0247 -->|"activates"| Cancer["Cancer"]
    KIAA0247 -->|"activates"| Aging["Aging"]
    KIAA0247 -->|"activates"| AUTOPHAGY["AUTOPHAGY"]
    KIAA0247 -->|"activates"| AND["AND"]
    KIAA0247 -->|"activates"| APOPTOSIS["APOPTOSIS"]
    TP53 -->|"upregulates"| KIAA0247
    GENES["GENES"] -->|"activates"| KIAA0247
    DNA["DNA"] -->|"activates"| KIAA0247
    P53["P53"] -->|"activates"| KIAA0247
    APOPTOSIS -->|"activates"| KIAA0247
    AUTOPHAGY -->|"activates"| KIAA0247
    CANCER["CANCER"] -->|"activates"| KIAA0247
    DRAGO["DRAGO"] -->|"activates"| KIAA0247

Outgoing (25)

Target	Relation	Type	Str
TP53	interacts_with	gene	0.90
DNA Damage Response	involved_in	process	0.90
tumor development	suppresses	process	0.90
cell death	promotes	process	0.85
TP53	associated_with	gene	0.85
Genomic Stability	associated_with	process	0.85
DNA damage response	mediates	process	0.80
growth suppression	promotes	phenotype	0.80
apoptosis	promotes	process	0.80
genomic stability	involved_in	process	0.75
Aging	activates	disease	0.65
Tumor	activates	disease	0.65
Cancer	activates	disease	0.65
CANCER	activates	gene	0.60
DRAGO	activates	gene	0.60
Autophagy	activates	pathway	0.60
AUTOPHAGY	activates	gene	0.60
Apoptosis	activates	pathway	0.60
APOPTOSIS	activates	gene	0.60
MIRNAS	activates	gene	0.60
Ras	activates	protein	0.60
DNA	activates	gene	0.60
GENES	activates	gene	0.60
P53	activates	gene	0.60
oxidative stress response	participates_in	pathway	0.60

Incoming (11)

Source	Relation	Type	Str
DRAGO	associated_with	gene	1.00
TP53	upregulates	gene	0.95
DNA damage	upregulates	process	0.90
APOPTOSIS	activates	gene	0.60
AUTOPHAGY	activates	gene	0.60
GENES	activates	gene	0.60
DNA	activates	gene	0.60
P53	activates	gene	0.60
CANCER	activates	gene	0.60
DRAGO	activates	gene	0.60
MIRNAS	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KIAA0247 in their description or question text

No additional research found