| Gene Symbol | VTI1B |
| Protein Type | Receptor |
| Function | VTI1B is a vesicle-SNARE (v-SNARE) protein essential for intracellular membrane fusion events: |
| Molecular Weight | 23 kDa |
| Pathways | Apoptosis, Exocytosis, Mitochondrial Function, Complement |
| Ensembl ID | ENSG00000106052 |
| GeneCards | VTI1B |
| Human Protein Atlas | VTI1B |
| Q-SNARE Properties | VTI1B is a Qa-SNARE (glutamine-containing SNARE) that contributes one or more "layers" to the SNARE pin |
| Complex Formation | VTI1B typically interacts with syntaxins and SNAP-25 family members |
| Zippering | Assembly of the SNARE complex proceeds from N- to C-terminus, driving membrane fusion |
| Trans-Golgi Network to Endosomes | VTI1B is involved in trafficking from the TGN to early endosomes |
| Endosomal Maturation | VTI1B participates in the conversion from early to late endosomes |
| Late Endosome-Lysosome Fusion | Critical for lysosomal function and degradation pathways |
| Autophagosome-Lysosome Fusion | Essential for autophagy completion |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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