gene 1,640 words KG: TRPM3
Contents

TRPM3 Gene - Transient Receptor Potential Channel

🧬 Gene Info
Gene SymbolTRPM3
AliasesPage for TRPM3 Gene
Chromosome9q21.11
Protein FamilyTRPM (Transient Receptor Potential Melastatin)
Protein TypeChannel
Functionencodes a calcium-permeable nonselective cation channel belonging to the TRPM (Transient Receptor Potential Melastatin) family.
Primary Expressionthe central nervous system, with particularly high expression in regions involved in temperature sensation and endocrine function
Molecular Weight168 kDa
PathwaysAkt
UniProt IDQ9BQY4
NCBI Gene ID80084
Ensembl IDENSG00000083099
OMIM608394
GeneCardsTRPM3
Human Protein AtlasTRPM3
Associated Diseasesneurodegeneration
InteractionsSRC, TRPA1
KG Connections10 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

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Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.98
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67

Related Analyses (9)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived

See Also (6)

Neurodegeneration
disease · KG edge: implicated_in
AKT1 Gene
gene · KG edge: regulates
CREBBP Gene
gene · KG edge: regulates
SCN8A Gene - Nav1.6
gene · KG edge: regulates
SRC Gene
gene · KG edge: inhibits

Knowledge Graph (10 edges)

TRPA1 inhibits TRPM3
SRC inhibits TRPM3
SCN8A regulates TRPM3
AKT1 regulates TRPM3
TRPM3 regulates CREBBP
TRPM2 implicated_in TRPM3
TRPM3 inhibits Ms
TRPM3 inhibits Migraine
TRPM3 regulates Akt
genes-trpm3 linked_to TRPM3

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