gene 557 words KG: TRPM2
Contents

TRPM2 - Transient Receptor Potential Melastatin 2

🧬 Gene Info
Gene SymbolTRPM2
Full NameTransient Receptor Potential Cation Channel Subfamily M Member 2
AliasesPage for TRPM2, Page for TRPM2 Protein, Transient Receptor Potential Melastatin 2
Chromosome21q22.12
Protein TypeChannel
Functionis a calcium-permeable cation channel activated by oxidative stress and ADP-ribose.
Molecular Weight203 kDa
Amino Acids1705 aa
PathwaysOxidative Stress
UniProt IDTRPM2
Ensembl IDENSG00000086848
GeneCardsTRPM2
Human Protein AtlasTRPM2
Associated DiseasesAls, Bipolar, Bipolar Disorder, BIPOLAR_DISORDER, Depression
InteractionsAMPK, AND, APOPTOSIS, ATG5, BECN1, CAMK2
KG Connections135 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Is disrupted sleep a cause or consequence of neurodegenerati
neurodegeneration · archived

See Also (15)

Bipolar Cells in Visual Processing
cell · KG edge: associated_with
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with
Genes
index · KG edge: associated_with

Knowledge Graph (12 edges)

TRPM2 associated_with BIPOLAR_DISORDER
HTR2A associated_with TRPM2
DISC1 associated_with TRPM2
FKBP5 associated_with TRPM2
NRG1 associated_with TRPM2
DAO associated_with TRPM2
BMAL1 associated_with TRPM2
GRM4 associated_with TRPM2
SYNGR1 associated_with TRPM2
BDNF associated_with TRPM2

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