gene 1,474 words KG: TK2
Contents

TK2 Gene

🧬 Gene Info
Gene SymbolTK2
Full NameThymidine Kinase 2
Protein TypeProtein
FunctionThymidine kinase 2 (TK2) is a mitochondrial enzyme that catalyzes the phosphorylation of thymidine, deoxyuridine, and deoxycytidine.
Molecular Weight62 kDa
Amino Acids265 aa
UniProt IDSearch UniProt
GeneCardsTK2
Human Protein AtlasTK2
Associated Diseasesneurodegeneration
KG Connections28 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Digital Twin-Guided Metabolic Reprogramming
Score: 0.55

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Mitochondria
entity · KG edge: associated_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with
Genes
index · KG edge: associated_with
DGUOK — Deoxyguanosine Kinase
gene · KG edge: associated_with

Knowledge Graph (12 edges)

POLG2 associated_with TK2
SLC25A4 associated_with TK2
MFN2 associated_with TK2
TYMP associated_with TK2
RRM2B associated_with TK2
TK2 associated_with SUCLA2
TK2 associated_with SUCLG1
TK2 associated_with TFAM
TK2 associated_with POLG
TK2 associated_with RNASEH1

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