gene 1,105 words KG: SUCLG1
Contents

SUCLG1 — Succinate-CoA Ligase GDP Forming Subunit Alpha

🧬 Gene Info
Gene SymbolSUCLG1
Full NameSuccinate-CoA Ligase GDP Forming Subunit Alpha
Chromosome2p11.2
Protein FamilySuccinate-CoA ligase family
Functionof 463 amino acids with a molecular weight of ~50 kDa
Molecular Weight50 kDa
Amino Acids463 aa
Exons13
PathwaysApoptosis, Immune Response, Nf-Κb
UniProt ID[P53567](https://www.uniprot.org/uniprot/P53567)
Ensembl IDENSG00000153558
OMIM605172
GeneCardsSUCLG1
Human Protein AtlasSUCLG1
Associated Diseasesneurodegeneration
InteractionsACO2, ALZHEIMER, ALZHEIMER'S DISEASE, APP, APP/PS1, ATP
KG Connections60 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (4)

APOE-Dependent Autophagy Restoration
Score: 0.85
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Autophagosome Maturation Checkpoint Control
Score: 0.71
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65

Related Analyses (3)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
GBA-Synuclein Loop Therapeutics for PD
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

ATP P2X3 Receptor Neurons
cell · KG edge: activates
Cardiac MIBG Scan for Parkinsonism
diagnostic · KG edge: regulates
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with
Genes
index · KG edge: associated_with
DGUOK — Deoxyguanosine Kinase
gene · KG edge: associated_with

Knowledge Graph (12 edges)

SUCLG1 regulates GAIN
SUCLG1 regulates TLR4
APP inhibits SUCLG1
SUCLG1 associated_with STX17
POLG2 associated_with SUCLG1
SLC25A4 associated_with SUCLG1
MFN2 associated_with SUCLG1
TYMP associated_with SUCLG1
RRM2B associated_with SUCLG1
TK2 associated_with SUCLG1

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