gene 958 words KG: SLC7A1
Contents

SLC7A1 Gene

🧬 Gene Info
Gene SymbolSLC7A1
Chromosome19p13.2
Protein TypeTransporter
Functionis a high-affinity transmembrane transporter that mediates cellular uptake of cationic amino acids, particularly L-arginine, L-lysine, and L-ornithine[@mann2003].
Amino Acids629 aa
Exons14
PathwaysFerroptosis
UniProt IDP30825
NCBI Gene ID6541
Ensembl IDENSG00000147614
GeneCardsSLC7A1
Human Protein AtlasSLC7A1
Associated DiseasesAlzheimer's disease, Parkinson's disease
KG Connections23 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (8)

ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.85
CYP46A1 Overexpression Gene Therapy
Score: 0.95
Transcriptional Autophagy-Lysosome Coupling
Score: 0.90
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.81
Senescence-Induced Lipid Peroxidation Spreading
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56
Blood-Brain Barrier SPM Shuttle System
Score: 0.53

Related Analyses (7)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: co_discussed
Ferroptosis Validation in Parkinson's Disease
experiment · KG edge: inhibits
Genes
index · KG edge: co_discussed
ACSL4 Gene - Acyl-CoA Synthetase Long Chain Family Memb
gene · KG edge: co_discussed

Knowledge Graph (12 edges)

ACSL4 co_discussed SLC7A1
GPX4 co_discussed SLC7A1
NRF2 co_discussed SLC7A1
SLC7A1 co_discussed SLC7A11
SLC7A1 co_discussed STING
NCOA4 co_discussed SLC7A1
OGT co_discussed SLC7A1
HDAC5 co_discussed SLC7A1
SLC7A1 co_discussed STAT6
SLC7A1 co_discussed TRIM2

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