gene 2,455 words KG: RAB39B
Contents

RAB39B Gene

🧬 Gene Info
Gene SymbolRAB39B
Full NameRAB39B, Member RAS Oncogene Family
Function1. Early endosome dynamics: Regulates cargo sorting and recycling from early endosomes
Primary Expressionthe brain, with highest levels in the substantia nigra, hippocampus, and cerebral cortex
Molecular Weight26 kDa
Amino Acids235 aa
Exons8
GeneCardsRAB39B
Human Protein AtlasRAB39B
Associated DiseasesAls, Autism, Ms, Parkinson, Parkinson's disease
InteractionsC9ORF72, PI3K
KG Connections25 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.98
APOE-Dependent Autophagy Restoration
Score: 0.88
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51

Related Analyses (5)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Parkinson Basal Ganglia Circuit
circuit · KG edge: associated_with
Neurodegeneration
disease · KG edge: implicated_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
c9orf72-als-ftd-phenotype-mechanism
general · KG edge: interacts_with
C9orf72 — Chromosome 9 Open Reading Frame 72
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

RAB39B interacts_with PI3K
RAB39B associated_with AKT
RAB39B interacts_with C9ORF72
PI3K interacts_with RAB39B
ATP13A2 associated_with RAB39B
ATXN2 associated_with RAB39B
DNAJC13 associated_with RAB39B
FBXO7 associated_with RAB39B
GBA associated_with RAB39B
GCH1 associated_with RAB39B

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