| Gene Symbol | PTK2 |
| Aliases | Page for PTK2 Gene, Page for PTK2 Protein |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 125 kDa |
| Amino Acids | 052 aa |
| Pathways | MAPK, PI3K |
| Ensembl ID | ENSG00000169398 |
| GeneCards | PTK2 |
| Human Protein Atlas | PTK2 |
| Central kinase domain | Catalytic domain with tyrosine kinase activity |
| MAPK/ERK pathway | Regulates cell proliferation and differentiation |
| PI3K/Akt pathway | Promotes cell survival and metabolic regulation |
| Rho GTPases | Controls cytoskeletal dynamics and cell migration |
| p130Cas/FAK | Mechanical signaling and focal adhesion turnover |
| Associated Diseases | Alzheimer's disease, Cancer, Carcinoma, Tumor |
| Interactions | AGING, AUTOPHAGY, CANCER, CASP3, CASS4, CDK2 |
| KG Connections | 50 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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