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gene 1,242 words KG: ORAI1
Contents

ORAI1 Gene

🧬 Gene Info
Gene SymbolORAI1
Full NameCalcium Release-Activated Calcium Channel Protein 1
Chromosome12q24.31
Primary ExpressionT cells, Mast cells, Neurons, Astrocytes, Platelets
Molecular Weight33 kDa
Amino Acids329 aa
PathwaysAngiogenesis, Notch
UniProt IDQ8WTG4
NCBI Gene ID84876
Ensembl IDENSG00000182578
OMIM610277
GeneCardsORAI1
Human Protein AtlasORAI1
Associated DiseasesAlzheimer's Disease, Parkinson's Disease, Immunodeficiency, Stroke
InteractionsNOTCH1, PIEZO1, STIM1
KG Connections39 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (5)

Mechanosensitive Ion Channel Reprogramming
Score: 0.70CYP46A1 Overexpression Gene Therapy
Score: 0.92Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69Extracellular Matrix Stiffness Modulation
Score: 0.69Quantum Coherence Disruption in Cellular Communication
Score: 0.63

Related Analyses (4)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedNeuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (5)

Notch and Gamma-Secretase Modulators for Parkinson's Di
company · KG edge: regulatesGenes
index · KG edge: regulatesNOTCH1 Gene
gene · KG edge: activatesPIEZO1 — Piezo Type Mechanosensitive Ion Channel Compon
gene · KG edge: activatesAngiogenesis Pathway
mechanism · KG edge: activates

Knowledge Graph (12 edges)

PIEZO1 regulates ORAI1
ORAI1 regulates PIEZO1
NOTCH1 regulates ORAI1
UBIQUITIN regulates ORAI1
ORAI1 regulates UBIQUITIN
NOTCH1 activates ORAI1
ORAI1 activates PIEZO1
ORAI1 activates UBIQUITIN
ORAI1 inhibits PIEZO1
ORAI1 associated_with PIEZO1

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