gene 509 words KG: NPTXR
Contents

NPTXR — Neuronal Pentraxin Receptor

🧬 Gene Info
Gene SymbolNPTXR
Full NameNeuronal Pentraxin Receptor
Protein TypeReceptor
FunctionNeuronal Pentraxin Receptor (NPTXR) is a membrane protein that serves as the primary receptor for the neuronal pentraxin family, including NPTX1 and NPTX2.
Subcellular Localizationboth pre- and postsynaptic membranes at excitatory synapses
Molecular Weight50 kDa
Ensembl IDENSG00000162591
GeneCardsNPTXR
Human Protein AtlasNPTXR
Associated DiseasesAls, Alzheimer, Dementia, Diabetes, Ms
InteractionsBDNF, DEMENTIA, ROS, TRKB
KG Connections19 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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Related Hypotheses (3)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed

See Also (10)

JAK Inhibitors in Parkinson's Disease
company · KG edge: associated_with
Neurodegeneration
disease · KG edge: implicated_in
IL6 (Redirect)
redirect · KG edge: associated_with
STAT3 (Redirect)
redirect · KG edge: associated_with
BDNF Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

NPTXR activates BDNF
NPTXR activates TRKB
IL6 associated_with NPTXR
NPTXR associated_with STAT3
ROS activates NPTXR
NPTXR activates DEMENTIA
NPTXR activates Aging
NPTXR activates Dementia
JAK associated_with NPTXR
NPTXR associated_with DEMENTIA

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