gene 2,756 words KG: ESRRB
Contents

ESRRB Gene

🧬 Gene Info
Gene SymbolESRRB
AliasesEstrogen-Related Receptor Beta
Chromosome14q24.3
Protein TypeReceptor
Functionis an orphan nuclear receptor that belongs to the estrogen-related receptor (ERR) subfamily of nuclear receptors.
Primary Expressionvarious peripheral tissues [6](https://pubmed
Amino Acids503 aa
PathwaysStem Cell
Ensembl IDENSG00000119715
GeneCardsESRRB
Human Protein AtlasESRRB
Associated Diseasesneurodegeneration
InteractionsCANCER, CDKN1A, MYC, SMAD2, SMAD7
KG Connections11 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (9)

Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.82
CYP46A1 Overexpression Gene Therapy
Score: 0.73
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Neurodegeneration
disease · KG edge: implicated_in
Tumor Necrosis Factor (TNF)
entity · KG edge: activates
CDKN1A — Cyclin-Dependent Kinase Inhibitor 1A
gene · KG edge: inhibits
MYC Gene
gene · KG edge: activates
SMAD2 Gene
gene · KG edge: inhibits

Knowledge Graph (11 edges)

SMAD7 activates ESRRB
SMAD2 inhibits ESRRB
ESRRB inhibits CDKN1A
ESRRB activates MYC
ESRRB activates CANCER
ESRRB activates Tumor
ESRRB contributes_to Prostate Cancer
ESRRB activates Cancer
ESRRB contributes_to Als
ESRRB contributes_to Breast Cancer

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.