gene 960 words KG: ELAVL4
Contents

ELAVL4 Gene

🧬 Gene Info
Gene SymbolELAVL4
Full NameELAV Like Neuron-Specific RNA Binding Protein 4
Chromosome1p31.3
FunctionELAVL4 encodes ELAV-like protein 4 (also known as HU antigen D), a neuron-specific RNA-binding protein.
Primary Expressionneurons of the central and peripheral nervous systems
Molecular Weight38 kDa
Amino Acids326 aa
PathwaysApoptosis, Autophagy, Glutamate Signaling, Stem Cell, glutamate signaling
UniProt ID[P26378](https://www.uniprot.org/uniprot/P26378)
Ensembl IDENSG00000162374
GeneCardsELAVL4
Human Protein AtlasELAVL4
Associated DiseasesALS, dementia, frontotemporal, neurodegeneration
InteractionsALS, APOPTOSIS, AUTOPHAGY, DEMENTIA, FUS, MAPT
KG Connections45 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

Related Hypotheses (10)

CYP46A1 Overexpression Gene Therapy
Score: 0.98
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Axonal RNA Transport Reconstitution
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
RNA Granule Nucleation Site Modulation
Score: 0.66
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Amyotrophic Lateral Sclerosis
redirect · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
glutamate
general · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
MAPT - Microtubule-Associated Protein Tau
gene · KG edge: activates

Knowledge Graph (12 edges)

ELAVL4 activates MAPT
TAU activates ELAVL4
ELAVL4 regulates MAPT
ELAVL4 activates TAU
FUS activates ELAVL4
ELAVL4 associated_with MAPT
ELAVL4 participates_in glutamate signaling
ELAVL4 co_mentioned MAPT
ELAVL4 co_expressed_with MAPT
ELAVL4 associated_with frontotemporal

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...