| Gene Symbol | C5 |
| Protein Family | Complement system |
| Function | The C5 gene encodes a component of the complement system, part of the innate immune system involved in inflammation and immune response. |
| Subcellular Localization | Plasma |
| Molecular Weight | 190 kDa |
| Pathways | Membrane Attack Complex |
| UniProt ID | P01031 |
| GeneCards | C5 |
| Human Protein Atlas | C5 |
| C5a | A potent anaphylatoxin and pro-inflammatory mediator |
| C5b | The initiating fragment for formation of the membrane attack complex (MAC) |
| Huntington's Disease | Elevated C5a levels have been observed in HD models and may contribute to disease progression. |
| Associated Diseases | neurodegeneration |
| Interactions | AQP4, C3, CD19, CR1 |
| KG Connections | 34 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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