gene 1,883 words KG: ATP1A2
Contents

ATP1A2 Gene

🧬 Gene Info
Gene SymbolATP1A2
Full NameATPase Na⁺/K⁺ Transporting Subunit Alpha 2
Chromosome1q21.3
Functionis a P-type ATPase that belongs to a family of ion pumps that transport cations across cellular membranes using ATP hydrolysis.
Molecular Weight112 kDa
Amino Acids1018 aa
UniProt IDP13637 (also P24720 isoform)
NCBI Gene ID476
Ensembl IDENSG00000118520
OMIM182340
GeneCardsATP1A2
Human Protein AtlasATP1A2
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsADCYAP1R1, CANCER, CLDN4, NTRK2, SCN4B, SLC17A7
KG Connections25 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (8)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
Aquaporin-4 Polarization Rescue
Score: 0.73
Axonal RNA Transport Reconstitution
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Astrocyte MCT1/MCT4 Ratio Disruption with Metabolic Uncoupli
Score: 0.67
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.67

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Synaptic Mitochondrial Resilience Enhancement for Parkinson'
validation · proposed · Score: 0.40

See Also (6)

Neurodegeneration
disease · KG edge: implicated_in
Genes
index · KG edge: associated_with
NTRK2 Gene
gene · KG edge: associated_with
SCN4B Gene - Sodium Voltage-Gated Channel Beta Subunit
gene · KG edge: associated_with
slc17a7 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

SCN4B associated_with ATP1A2
SLC17A7 associated_with ATP1A2
NTRK2 associated_with ATP1A2
ATP1A2 associated_with NTRK2
ATP1A2 associated_with SCN4B
SCN4B interacts_with ATP1A2
NTRK2 interacts_with ATP1A2
ATP1A2 interacts_with SLC17A7
ATP1A2 interacts_with NTRK2
ATP1A2 interacts_with SCN4B

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)