| Gene Symbol | APPBP2 |
| Full Name | Amyloid Precursor Protein Binding Protein 2 |
| Chromosome | 16q24.1 |
| Function | is a gene located on chromosome 16q24.1 that encodes a protein that binds to the cytoplasmic domain of Amyloid Precursor Protein (APP) |
| Primary Expression | Cerebral cortex, Hippocampus, Cerebellum, Testis |
| Subcellular Localization | , trafficking, and processing through proteasomal and autophagy-mediated pathways. APPBP2 is expressed in neurons and gl |
| Molecular Weight | 59 kDa |
| UniProt ID | Q92688 |
| NCBI Gene ID | 10513 |
| Ensembl ID | ENSG00000142541 |
| OMIM | 604390 |
| GeneCards | APPBP2 |
| Human Protein Atlas | APPBP2 |
| APP (Amyloid Precursor Protein) | Primary substrate and interaction partner |
| PSEN1 and PSEN2 | Presenilin components of γ-secretase complex affecting APP processing |
| Interactions | APP, BACE1, BIN1, CLU, PICALM, PSEN1 |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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