gene 1,784 words KG: ent-gene-bf93c073
Contents

AIM2 Gene

🧬 Gene Info
Gene SymbolAIM2
Protein FamilyAIM2-like receptor (ALR)
FunctionAIM2 functions as a cytosolic DNA sensor forming the AIM2 inflammasome.
Subcellular LocalizationCytoplasm
Molecular Weight39 kDa
Amino Acids200 aa
PathwaysApoptosis, Autophagy, Cholesterol, Ferroptosis, Immune Response
UniProt IDQ9WZE6
GeneCardsAIM2
Human Protein AtlasAIM2
Associated DiseasesAls, Atherosclerosis, Cancer, Dementia, Infection
InteractionsACTB, Actin, ALZHEIMER, AMPK, AND, APOPTOSIS
KG Connections403 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.71
Microbial Inflammasome Priming Prevention
Score: 0.65
Autophagosome Maturation Checkpoint Control
Score: 0.71
Lysosomal Positioning Dynamics Modulation
Score: 0.69
LRP1-Dependent Tau Uptake Disruption
Score: 0.60
Blood-Brain Barrier SPM Shuttle System
Score: 0.53

Related Analyses (3)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Packard Center for ALS Research
institution · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
ACTB Gene
gene · KG edge: activates
ATG16L1 - Autophagy Related 16 Like 1
gene · KG edge: activates
ATG14 Gene
gene · KG edge: activates

Knowledge Graph (2 edges)

ent-gene-bf93c073 data_in benchmark_ot_ad_answer_key:AIM2
benchmark_ot_ad_answer_key:AIM2 data_in ent-gene-bf93c073

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.