gene 725 words KG: E2F1
Contents

E2F1 Gene

🧬 Gene Info
Gene SymbolE2F1
Chromosome20q11.22
Protein TypeTranscription Factor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionproliferating neural precursors - Differentiated neurons: Low expression - Glia: Variable expression - Developmental: High during neurogen
Molecular Weight47 kDa
Exons9 coding exons
PathwaysApoptosis, Autophagy, Cell Cycle
Ensembl IDENSG00000101412
GeneCardsE2F1
Human Protein AtlasE2F1
LocationChromosome 20q11.22
Gene Length~11 kb
Alternative SplicingMultiple isoforms
Associated Diseasescerebral_ischemia-reperfusion_injury
InteractionsAKT, AND, APOPTOSIS, App, APP, APP/PS1
KG Connections123 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

E2F7 activates E2F1
E2F8 activates E2F1
E2F1 activates E2F2
E2F1 activates E2F3
E2F1 activates RAB37
E2F1 activates E2F7
E2F1 activates HMGB1
E2F1 activates E2F8
E2F1 associated_with BECN1
E2F1 activates PI3K

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