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disease 746 words KG: ent-dise-42612378
Contents

Investment Landscape: Parkinson's Disease

Disease Info
PHASE1337
PHASE1, PHASE2108
PHASE2485
PHASE2, PHASE354
PHASE3253
PHASE4184
NA2006
Not Applicable1128
RECRUITING684
ACTIVE_NOT_RECRUITING148
NOT_YET_RECRUITING229
COMPLETED2369
DatabasesOMIMOrphanetClinicalTrialsPubMed

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OMIMMeSHWikipedia

Related Hypotheses (10)

Purinergic Signaling Polarization Control
Score: 0.71Mechanosensitive Ion Channel Reprogramming
Score: 0.70Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76APOE-TREM2 Interaction Modulation
Score: 0.74TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69Microbial Inflammasome Priming Prevention
Score: 0.65TREM2-mediated microglial tau clearance enhancement
Score: 0.62TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58TREM2-Dependent Microglial Senescence Transition
Score: 0.58

Related Analyses (15)

Synaptic pruning by microglia in early AD
neurodegeneration · archivedWhat are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedTREM2 agonism vs antagonism in DAM microglia
neurodegeneration · completedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · completed

Related Experiments (30)

Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40Down Syndrome Alzheimer's Disease: Mechanisms and Therapeuti
clinical · proposed · Score: 0.40iPSC-derived astrocyte-neuron co-culture mitochondrial trans
exploratory · proposed · Score: 0.90Longitudinal TLR2 reporter gene study in α-synuclein mice
validation · proposed · Score: 0.90Dexamethasone treatment study in α-synuclein mice
validation · proposed · Score: 0.85

See Also (15)

Alpha-Synuclein PET Imaging and Biomarker Advances
biomarker · Pages share 3 hypothesesAlpha-Synuclein Seeding Assays (RT-QuIC and PMCA)
biomarker · Pages share 3 hypothesesBlood-Based Biomarkers for Neurodegeneration
biomarker · Pages share 3 hypothesesBlood p-Tau181 and p-Tau217 Elevated in Systemic Amyloi
biomarker · Pages share 3 hypothesesCSF Biomarkers for Corticobasal Syndrome and Progressiv
biomarker · Pages share 3 hypotheses

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