Contents

CSF Neurofilament Light Chain (NfL) in Neurodegeneration

🔬 Protein Info

Gene Symbol	CSF
Heavy chain (NF-H)	200-220 kDa, heavily phosphorylated
Medium chain (NF-M)	160-170 kDa
Light chain (NfL)	61-70 kDa, most soluble and abundant in CSF
α-internexin	Present in CNS neurons
Peripherin	Peripheral nervous system specific
Associated Diseases	MULTIPLE SCLEROSIS
Known Drugs/Compounds	ADUCANUMAB
KG Connections	125 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING