protein 932 words KG: CREB1
Contents

CREB1 Protein

🔬 Protein Info
Gene SymbolCREB1
Full NamecAMP Response Element Binding Protein 1
Chromosome2q33.3
Protein TypeTranscription Factor
FunctionCREB1 is a transcription factor that regulates gene expression in response to cAMP and calcium signaling.
Primary Expressionbrain, with high levels in hippocampus, cortex, and striatum
Subcellular Localization</th><td>Nucleus</td></tr>
Molecular Weight37 kDa
PathwaysApoptosis, CREB signaling, MAPK signaling, Mapk, Oxidative Phosphorylation
UniProt IDP16220
NCBI Gene ID1385
Ensembl IDENSG00000108748
OMIM123810
GeneCardsCREB1
Human Protein AtlasCREB1
Associated DiseasesBreast Cancer, Cancer, neurodegeneration
InteractionsACTB, Actin, AMPK, APOE, APOPTOSIS, APP
KG Connections243 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (18)

CREB-Dependent Differential Complement Regulator Positioning
Score: 0.00
Gamma Oscillation Entrainment Enhances lncRNA-9969-Mediated
Score: 0.87
Activity-Dependent Synaptic Tagging via CREB-BDNF-TrkB Signa
Score: 0.65
Epigenetic Memory Reprogramming for Alzheimer's Disease
Score: 0.61
Gamma-Entrained PV Interneuron Networks Enable Precision p-t
Score: 0.55
Gamma-Entrained PV Interneurons Enable p-tau217-Guided Preci
Score: 0.55
Alpha-Beta Oscillation Coupling Enhances lncRNA-9969-Mediate
Score: 0.46
Alpha-Beta Oscillation Entrainment Enhances lncRNA-9969-Medi
Score: 0.43
Theta-Gamma Coupling Modulates lncRNA-9969-Mediated Mitochon
Score: 0.42
Alpha-Theta Oscillation Modulation Enhances lncRNA-9969-Medi
Score: 0.42
cAMP/PKA-Dependent Transcription Factor Activation via Nutri
Score: 0.42
CREB-Mediated Differential CD55/CD46 Expression Creates Acti
Score: 0.38
Astrocyte-Mediated Synaptic Tagging via CREB-S100B-RAGE Sign
Score: 0.38
CREB-Mediated Differential CD55/CD46 Expression Creates Acti
Score: 0.38
Activity-Dependent Synaptic Tagging via CREB-IGF1-IGF1R Sign
Score: 0.38
CREB1-Induced lncRNA-9969 Selectively Sequesters miR-6361 Th
Score: 0.38
CREB1-Induced lncRNA-9969 Selectively Binds miR-6361 Through
Score: 0.38
Theta-Alpha Oscillation Entrainment Enhances lncRNA-9969-Med
Score: 0.38

Knowledge Graph (12 edges)

TRIM27 interacts_with CREB1
CREB1 activates TFEB
CREB1 regulates PIEZO1
REST activates CREB1
P38 activates CREB1
CREB1 activates PPARGC1A
EP300 interacts_with CREB1
MET expressed_in CREB1
CREBBP activates CREB1
BDNF co_discussed CREB1

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