Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about B4GANLT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | B4GANLT1 |
| Key Genes/Proteins | AGING, COMPLEMENT, Cytokine, CYTOKINES, DNA, GENES |
| Related Diseases | Aging, Als, ALS |
| Related Pathways | Complement, Complement System, Ganglioside Metabolism |
graph TD
B4GANLT1["B4GANLT1"]
B4GANLT1 -->|"encodes"| Ganglioside_GM2_GD2["Ganglioside GM2/GD2"]
B4GANLT1 -->|"involved_in"| Ganglioside_Metabolism["Ganglioside Metabolism"]
B4GANLT1 -->|"product_of"| Gangliosides["Gangliosides"]
B4GANLT1 -->|"expressed in"| Neuroinflammation["Neuroinflammation"]
B4GANLT1 -->|"expressed in"| ALS["ALS"]
B4GANLT1 -->|"expressed in"| Aging["Aging"]
B4GANLT1 -->|"expressed in"| Inflammation["Inflammation"]
B4GANLT1 -->|"expressed in"| Als["Als"]
AGING["AGING"] -->|"expressed in"| B4GANLT1
NEUROINFLAMMATION["NEUROINFLAMMATION"] -->|"expressed in"| B4GANLT1
DNA["DNA"] -->|"expressed in"| B4GANLT1
COMPLEMENT["COMPLEMENT"] -->|"expressed in"| B4GANLT1
INFLAMMATION["INFLAMMATION"] -->|"expressed in"| B4GANLT1
CYTOKINES["CYTOKINES"] -->|"expressed in"| B4GANLT1
GFAP["GFAP"] -->|"expressed in"| B4GANLT1
NEURON["NEURON"] -->|"expressed in"| B4GANLT1| Target | Relation | Type | Str |
|---|---|---|---|
| Ganglioside GM2/GD2 | encodes | compound | 0.95 |
| Ganglioside Metabolism | involved_in | pathway | 0.85 |
| Gangliosides | product_of | compound | 0.85 |
| Neurodegeneration | associated_with | disease | 0.65 |
| Neuroinflammation | expressed_in | disease | 0.65 |
| ALS | expressed_in | disease | 0.65 |
| Aging | expressed_in | disease | 0.65 |
| Inflammation | expressed_in | disease | 0.65 |
| Als | expressed_in | disease | 0.65 |
| GFAP | expressed_in | gene | 0.60 |
| CYTOKINES | expressed_in | gene | 0.60 |
| ST8SIA1 | associated_with | gene | 0.60 |
| INFLAMMATION | expressed_in | gene | 0.60 |
| DNA | expressed_in | gene | 0.60 |
| COMPLEMENT | expressed_in | gene | 0.60 |
| AGING | expressed_in | gene | 0.60 |
| Sphingolipid | expressed_in | pathway | 0.60 |
| Complement | expressed_in | pathway | 0.60 |
| NEURON | expressed_in | gene | 0.60 |
| neurodegeneration | associated_with | disease | 0.60 |
| Complement System | expressed_in | pathway | 0.60 |
| Cytokine | expressed_in | protein | 0.60 |
| Ras | expressed_in | protein | 0.60 |
| Neuron | expressed_in | cell_type | 0.55 |
| Spinal Cord | expressed_in | brain_region | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| NEURON | expressed_in | gene | 0.60 |
| AGING | expressed_in | gene | 0.60 |
| NEURODEGENERATION | associated_with | gene | 0.60 |
| NEUROINFLAMMATION | expressed_in | gene | 0.60 |
| DNA | expressed_in | gene | 0.60 |
| COMPLEMENT | expressed_in | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| INFLAMMATION | expressed_in | gene | 0.60 |
| CYTOKINES | expressed_in | gene | 0.60 |
| GFAP | expressed_in | gene | 0.60 |
| ST8SIA1 | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning B4GANLT1 in their description or question text
No additional research found