gene 2,204 words KG: FOXP3
Contents

FOXP3 (Forkhead Box P3)

🧬 Gene Info
Gene SymbolFOXP3
Full NameFOXP3 (Forkhead Box P3)
ChromosomeXp11.23
Protein TypeTranscription Factor
Target ClassTranscription Factor
FunctionTranscription factor modulation - no direct small molecule binding
Mechanism of ActionTranscription factor modulation - no direct small molecule binding
DruggabilityLow (0.35)
Clinical StagePhase I
Amino Acids431 aa
PathwaysApoptosis, Complement, Hedgehog, Immune Response, Mtor
UniProt IDA0A494BZV0
GeneCardsFOXP3
Human Protein AtlasFOXP3
Associated DiseasesAls, Alzheimer, Autoimmune, cancer
Known Drugs/Compoundspaeoniflorin, Paeoniflorin
InteractionsACHE, ACOD1, AIF1, AKT, AMPK, AND
SciDEX TargetView Target Profile (2 clinical trials)
KG Connections568 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

Aryl Hydrocarbon Receptor (AHR) Activation in B Cells Determ
Score: 0.70
Ocular Immune Privilege Extension
Score: 0.69

Knowledge Graph (12 edges)

FOXP3 interacts_with TGFB1
TGFB1 interacts_with FOXP3
FOXP3 co_discussed TNFA
FOXP3 co_discussed PPARGC1A
FOXP3 co_discussed PRKAA1
FOXP3 co_discussed NR3C1
FOXP3 co_discussed DRD2
FOXP3 co_discussed CHR2
FOXP3 co_discussed CLOCK
FOXP3 co_discussed CRH

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