protein

CLATHRIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CLATHRIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

20Connections

0Hypotheses

0Analyses

12Outgoing

8Incoming

0Experiments

0Debates

Summary

Page for Clathrin Protein

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🔬 Protein Info

Gene Symbol	CLATHRIN
Function	Clathrin Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Molecular Weight	191 kDa
Amino Acids	675 aa
Pathways	Endocytosis
GeneCards	CLATHRIN
Human Protein Atlas	CLATHRIN
Interactions	BIN1, CD2AP, EGFR, PIEZO1, SORL1
KG Connections	18 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

flowchart TD
    N0["CLATHRIN"]
    N1["Endocytosis"]
    N0 -->|"activates"| N1
    N0 -->|"associated with"| N1
    N2["SYNUCLEIN"]
    N0 -->|"regulates"| N2
    N3["alpha-SYNUCLEIN"]
    N0 -->|"regulates"| N3
    N4["CD2AP"]
    N0 -->|"interacts with"| N4
    N5["Genes"]
    N0 -->|"interacts with"| N5
    N0 -->|"interacts with"| N1
    N6["TAU PATHOLOGY"]
    N0 -->|"interacts with"| N6
    N7["ENDOSOME"]
    N0 -->|"interacts with"| N7
    N8["RAB11"]
    N0 -->|"associated with"| N8
    N0 -->|"activates"| N5
    N9["atherosclerosis"]
    N0 -->|"activates"| N9
    N0 -->|"regulates"| N1
    N10["ENDOSOMES"]
    N0 -->|"regulates"| N10

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 pathway
    class N4 protein
    class N8 gene
    class N9 disease

Outgoing (12)

Target	Relation	Type	Str
Endocytosis	associated_with	pathway	0.50
SYNUCLEIN	regulates	concept	0.50
α-SYNUCLEIN	regulates	concept	0.50
CD2AP	interacts_with	protein	0.50
Endocytosis	interacts_with	pathway	0.50
TAU PATHOLOGY	interacts_with	concept	0.50
ENDOSOME	interacts_with	concept	0.50
Endocytosis	regulates	pathway	0.50
ENDOSOMES	regulates	concept	0.50
Endocytosis	activates	pathway	0.50
RAB11	associated_with	gene	0.50
atherosclerosis	activates	disease	0.50

Incoming (8)

Source	Relation	Type	Str
34544422	is required for	paper	0.90
BIN1	interacts_with	protein	0.60
SORL1	interacts_with	gene	0.50
BIN1	interacts_with	gene	0.50
EGFR	activates	gene	0.50
PIEZO1	activates	gene	0.50
FLOT1	associated_with	gene	0.50
BIN1	associated_with	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CLATHRIN in their description or question text

No additional research found