Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TNFR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Dementia | associated_with | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Methamphetamine | upregulates | drug | 0.85 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| TNFRSF25-Mediated Aging Exosome Pathway Inhibition | 0.587 | neurodegeneration | Gene expression changes in aging mouse b |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Death receptor 3: A paradoxical biomarker and therapeutic target in pan-cancer. [PMID:41605339] | Fang W, Du J, Xu Z, Liu Q, Liu Y et al. | Crit Rev Oncol Hematol | 2026 | 0 |
| Homocysteine as a biomarker in arthritis and depression: Evidence from NHANES an [PMID:41693749] | Deng C, He Z, Zhu X | SAGE Open Med | 2026 | 0 |
| The involvement of TNFRSF25 in age-related hearing loss. [PMID:41882185] | Roche MV, Tang PC, Yan D, De Marchena MR | Hum Genet | 2026 | 0 |
| Maternal immune activation perturbs intestinal niche through microbial glyceroph [PMID:41926285] | Chang H, Zhu X, Shen C, Xu X, Ni Y et al | Cell Rep | 2026 | 0 |
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning TNFR in their description or question text
No additional research found