gene

TMEM230

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TMEM230: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

22Connections

0Hypotheses

0Analyses

19Outgoing

3Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	TMEM230
Full Name	Transmembrane Protein 230
Chromosome	20p13
Protein Family	TMEM230/C20orf30 family
Function	encodes a transmembrane protein localized primarily to synaptic vesicles, endosomes, and mitochondria [@tmem230_pd].
Molecular Weight	25 kDa
Amino Acids	175 aa
Pathways	Apoptosis, Dna Repair, Glycolysis, Oxidative Phosphorylation, glycosylation
UniProt ID	Q9H0Y7
NCBI Gene ID	138802
Ensembl ID	ENSG00000167840
GeneCards	TMEM230
Human Protein Atlas	TMEM230
Associated Diseases	Parkinson's disease
Interactions	AKT, MTOR, PI3K
KG Connections	22 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: TMEM230 — AlphaFold Q9H0Y7 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

TMEM230 Gene

gene · 2376 words

→

TMEM230 Protein

protein · 1530 words

→

Pathway Diagram

graph TD
    TMEM230["TMEM230"]
    glycosylation["glycosylation"]
    TMEM230 -->|"regulates"| glycosylation
    unfolded_protein_response["unfolded protein response"]
    TMEM230 -->|"regulates"| unfolded_protein_response
    neurodegeneration["neurodegeneration"]
    TMEM230 -->|"implicated in"| neurodegeneration
    style TMEM230 fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7

Outgoing (19)

Target	Relation	Type	Str
glycosylation	regulates	process	0.85
glycan synthesis	regulates	process	0.80
glycan processing	regulates	process	0.80
unfolded protein response	regulates	process	0.80
Autoimmune	inhibits	disease	0.65
Aging	regulates	disease	0.65
Tumor	regulates	disease	0.65
Senescence	regulates	disease	0.65
Parkinson	regulates	disease	0.65
Neurodegeneration	regulates	disease	0.65
Cancer	regulates	disease	0.65
Alzheimer	regulates	disease	0.65
Apoptosis	regulates	pathway	0.60
Unfolded Protein Response	inhibits	pathway	0.60
Glycolysis	regulates	pathway	0.60
Oxidative Phosphorylation	regulates	pathway	0.60
Mtor	inhibits	pathway	0.60
Dna Repair	regulates	pathway	0.60
PI3K-AKT-mTOR signaling	participates_in	pathway	0.60

Incoming (3)

Source	Relation	Type	Str
AKT	inhibits	gene	0.60
PI3K	inhibits	gene	0.60
MTOR	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TMEM230 in their description or question text

No additional research found