Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SYNAPSIN2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SYNAPSIN2 |
| Key Genes/Proteins | BRAIN INFLAMMATION, Chemokine, CX3CR1, EPILEPSY, GEPHYRIN, INFLAMMATION |
| Related Diseases | Als, ALS, Epilepsy, Inflammation |
| Related Pathways | Neurogenesis, Synaptic Vesicle |
Knowledge base pages for this entity
graph TD
SYNAPSIN2["SYNAPSIN2"]
SYNAPSIN2 -->|"inhibits"| Tumor["Tumor"]
SYNAPSIN2 -->|"inhibits"| ALS["ALS"]
SYNAPSIN2 -->|"inhibits"| Epilepsy["Epilepsy"]
SYNAPSIN2 -->|"inhibits"| Als["Als"]
SYNAPSIN2 -->|"inhibits"| GEPHYRIN["GEPHYRIN"]
SYNAPSIN2 -->|"inhibits"| CX3CR1["CX3CR1"]
SYNAPSIN2 -->|"inhibits"| Synaptic_Vesicle["Synaptic Vesicle"]
SYNAPSIN2 -->|"inhibits"| EPILEPSY["EPILEPSY"]
EPILEPSY -->|"inhibits"| SYNAPSIN2
GEPHYRIN -->|"inhibits"| SYNAPSIN2| Target | Relation | Type | Str |
|---|---|---|---|
| Tumor | inhibits | disease | 0.65 |
| Als | inhibits | disease | 0.65 |
| ALS | inhibits | disease | 0.65 |
| Epilepsy | inhibits | disease | 0.65 |
| Inflammation | associated_with | disease | 0.65 |
| BRAIN INFLAMMATION | associated_with | gene | 0.60 |
| Neurogenesis | associated_with | pathway | 0.60 |
| Interleukin | inhibits | protein | 0.60 |
| Chemokine | inhibits | protein | 0.60 |
| EPILEPSY | inhibits | gene | 0.60 |
| Microglia | inhibits | cell_type | 0.60 |
| GEPHYRIN | inhibits | gene | 0.60 |
| CX3CR1 | inhibits | gene | 0.60 |
| Synaptic Vesicle | inhibits | pathway | 0.60 |
| Microglia | expressed_in | cell_type | 0.55 |
| Cortex | expressed_in | brain_region | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GEPHYRIN | inhibits | gene | 0.60 |
| EPILEPSY | inhibits | gene | 0.60 |
| INFLAMMATION | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SYNAPSIN2 in their description or question text
No additional research found