Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RS6656401: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | RS6656401 |
| Key Genes/Proteins | ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AND, C1Q, C1S |
| Related Diseases | Alzheimer |
| Related Pathways | Amyloid, Complement |
graph TD
RS6656401["RS6656401"]
RS6656401 -->|"regulates"| CR1["CR1"]
RS6656401 -->|"implicated in"| RS3919533["RS3919533"]
RS6656401 -->|"implicated in"| CFH["CFH"]
RS6656401 -->|"implicated in"| CLU["CLU"]
RS6656401 -->|"implicated in"| CLUSTERIN["CLUSTERIN"]
RS6656401 -->|"implicated in"| RS6664877["RS6664877"]
RS6656401 -->|"implicated in"| C1S["C1S"]| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:RS6656401 | data_in | dataset_row | 0.00 |
| SCR1 | regulates | protein | 0.80 |
| CR1 | regulates | protein | 0.70 |
| Alzheimer | associated_with | disease | 0.65 |
| Neurodegeneration | associated_with | disease | 0.65 |
| Complement | associated_with | pathway | 0.60 |
| Amyloid | associated_with | pathway | 0.60 |
| RS3919533 | associated_with | gene | 0.60 |
| CFH | associated_with | gene | 0.60 |
| CLU | associated_with | gene | 0.60 |
| CR1 | associated_with | gene | 0.60 |
| CLUSTERIN | associated_with | gene | 0.60 |
| RS6664877 | associated_with | gene | 0.60 |
| C1S | associated_with | gene | 0.60 |
| NEURODEGENERATION | associated_with | gene | 0.60 |
| COMPLEMENT | associated_with | gene | 0.60 |
| ALZHEIMER | associated_with | gene | 0.60 |
| AMYLOID | associated_with | gene | 0.60 |
| C1Q | associated_with | gene | 0.60 |
| ALZHEIMER'S DISEASE | associated_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:RS6656401 | data_in | dataset_row | 0.00 |
| ent-gene-6a42454e | has_risk_variant | gene | 0.00 |
| AMYLOID | associated_with | gene | 0.60 |
| ALZHEIMER | associated_with | gene | 0.60 |
| CLUSTERIN | associated_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| CR1 | associated_with | gene | 0.60 |
| AND | associated_with | gene | 0.60 |
| RS6664877 | associated_with | gene | 0.60 |
| C1Q | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RS6656401 in their description or question text
No additional research found