gene

RNF2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RNF2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

11Outgoing

5Incoming

0Experiments

0Debates

Summary

RNF2

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🧬 Gene Info

Gene Symbol	RNF2
Full Name	Ring Finger Protein 2
Chromosome	1q25.3
Function	is a human gene
Pathways	Apoptosis, Autophagy, Cell Cycle, Mtor, Tgf-Β
UniProt ID	Q99496
Ensembl ID	ENSG00000121481
OMIM	608985
GeneCards	RNF2
Human Protein Atlas	RNF2
Associated Diseases	Cancer
Interactions	AND, APOPTOSIS, AUTOPHAGY, CYTOKINES, MTOR
KG Connections	16 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: RNF2 — AlphaFold Q99496 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

RNF2

gene · 960 words

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RNF20

gene · 651 words

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Pathway Diagram

graph TD
    RNF2["RNF2"]
    Fibrosis{"Fibrosis"}
    RNF2 -->|"activates"| Fibrosis
    Cancer{"Cancer"}
    RNF2 -->|"associated_with"| Cancer
    RB1["RB1"]
    RNF2 -->|"regulates"| RB1
    CANCER["CANCER"]
    RNF2 -->|"associated_with"| CANCER
    P16["P16"]
    RNF2 -->|"regulates"| P16
    MTOR["MTOR"]
    RNF2 -->|"activates"| MTOR
    Tgf(["Tgf-Beta"])
    RNF2 -->|"activates"| Tgf
    Autophagy(["Autophagy"])
    RNF2 -->|"activates"| Autophagy
    Apoptosis(["Apoptosis"])
    RNF2 -->|"activates"| Apoptosis
    Cell_Cycle(["Cell Cycle"])
    RNF2 -->|"activates"| Cell_Cycle
    Mtor(["Mtor"])
    RNF2 -->|"activates"| Mtor
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"activates"| RNF2
    CDK4["CDK4"]
    CDK4 -->|"regulates"| RNF2
    AND["AND"]
    AND -->|"activates"| RNF2
    CYTOKINES["CYTOKINES"]
    CYTOKINES -->|"activates"| RNF2

Outgoing (11)

Target	Relation	Type	Str
Cancer	associated_with	disease	0.65
Fibrosis	activates	disease	0.65
Tgf-Β	activates	pathway	0.60
Autophagy	activates	pathway	0.60
Apoptosis	activates	pathway	0.60
Cell Cycle	activates	pathway	0.60
Mtor	activates	pathway	0.60
RB1	regulates	gene	0.60
CANCER	associated_with	gene	0.60
MTOR	activates	gene	0.60
P16	regulates	gene	0.60

Incoming (5)

Source	Relation	Type	Str
APOPTOSIS	activates	gene	0.60
CYTOKINES	activates	gene	0.60
AUTOPHAGY	activates	gene	0.60
AND	activates	gene	0.60
CDK4	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RNF2 in their description or question text

No additional research found