protein

RAB3BPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RAB3BPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

RAB3B (Ras-Related Protein Rab-3B) is a neuronal small GTPase that plays a critical role in regulating synaptic vesicle trafficking and neurotransmitter release.

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🔬 Protein Info

Gene Symbol	RAB3BPROTEIN
Chromosome	1p31.1
Function	is a neuronal small GTPase that plays a critical role in regulating synaptic vesicle trafficking and neurotransmitter release.
Primary Expression	neurons and neuroendocrine cells, where it functions as a molecular switch controlling vesicle dynamics essential for synaptic communication
Subcellular Localization	and membrane association specificity. This region shows greater sequence variation between Rab family members compared t
GeneCards	RAB3BPROTEIN
Human Protein Atlas	RAB3BPROTEIN
Effector region (residues 75-95)	A variable region that mediates interactions with downstream effector proteins. The sequence and structure of this region determine effector specificity among different Rab proteins.
Associated Diseases	Als, Alzheimer, dementia, frontotemporal, neurodegeneration
Interactions	CALB2, CHRNA6, GFAP
KG Connections	55 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

rab3b-protein

protein · 2516 words

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Pathway Diagram

graph TD
    RAB3BPROTEIN["RAB3BPROTEIN"]
    neurodegeneration["neurodegeneration"]
    RAB3BPROTEIN -->|"implicated_in"| neurodegeneration
    style RAB3BPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning RAB3BPROTEIN in their description or question text

No additional research found