| Gene Symbol | RAB3BPROTEIN |
| Chromosome | 1p31.1 |
| Function | is a neuronal small GTPase that plays a critical role in regulating synaptic vesicle trafficking and neurotransmitter release. |
| Primary Expression | neurons and neuroendocrine cells, where it functions as a molecular switch controlling vesicle dynamics essential for synaptic communication |
| Subcellular Localization | and membrane association specificity. This region shows greater sequence variation between Rab family members compared t |
| GeneCards | RAB3BPROTEIN |
| Human Protein Atlas | RAB3BPROTEIN |
| Effector region (residues 75-95) | A variable region that mediates interactions with downstream effector proteins. The sequence and structure of this region determine effector specificity among different Rab proteins. |
| Associated Diseases | Als, Alzheimer, dementia, frontotemporal, neurodegeneration |
| Interactions | CALB2, CHRNA6, GFAP |
| KG Connections | 55 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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