Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about OLFACTORY BULB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | OLFACTORY BULB |
| Key Genes/Proteins | ALPHA-SYNUCLEIN, TH |
| Related Diseases | AGING, LEWY BODIES, NEUROGENESIS, PARKINSON, PARKINSON'S DISEASE |
Knowledge base pages for this entity
graph TD
OLFACTORY_BULB[OLFACTORY BULB]
OLFACTORY_BULB -->|involved_in| SNCA[SNCA]
OLFACTORY_BULB -->|activates| PROTEIN_AGGREGATION[PROTEIN AGGREGATION]
OLFACTORY_BULB -->|activates| PARKINSON_S_DISEASE[PARKINSON'S DISEASE]
OLFACTORY_BULB -->|expressed in| SUBSTANTIA_NIGRA[SUBSTANTIA NIGRA]
OLFACTORY_BULB -->|expressed in| THALAMUS[THALAMUS]
Parkinson_s_disease[Parkinson's disease] -->|affects| OLFACTORY_BULB
neurodegeneration[neurodegeneration] -->|affects| OLFACTORY_BULB
TH[TH] -->|expressed in| OLFACTORY_BULB
aging[aging] -->|affects| OLFACTORY_BULB
NEURON[NEURON] -->|expressed in| OLFACTORY_BULB
ALPHA_SYNUCLEIN[ALPHA-SYNUCLEIN] -->|activates| OLFACTORY_BULB
AMYGDALA[AMYGDALA] -->|causes| OLFACTORY_BULB
CEREBRAL_CORTEX[CEREBRAL CORTEX] -->|expressed in| OLFACTORY_BULB
HIPPOCAMPUS[HIPPOCAMPUS] -->|expressed in| OLFACTORY_BULB| Target | Relation | Type | Str |
|---|---|---|---|
| SNCA | involved_in | protein | 0.75 |
| Alpha-Synuclein Aggregation | associated_with | process | 0.70 |
| AGING | associated_with | phenotype | 0.50 |
| NEUROGENESIS | associated_with | phenotype | 0.50 |
| TH | associated_with | gene | 0.50 |
| NEURONS | associated_with | cell_type | 0.45 |
| PARKINSON | associated_with | disease | 0.45 |
| LEWY BODIES | associated_with | phenotype | 0.45 |
| PROTEIN AGGREGATION | activates | process | 0.35 |
| THALAMUS | expressed_in | brain_region | 0.35 |
| SUBSTANTIA NIGRA | expressed_in | brain_region | 0.35 |
| PARKINSON'S DISEASE | activates | disease | 0.35 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Parkinson's disease | affects | disease | 0.80 |
| TH | expressed_in | gene | 0.60 |
| aging | affects | disease | 0.60 |
| neurodegeneration | affects | disease | 0.60 |
| NEURON | expressed_in | cell_type | 0.50 |
| PROTEIN AGGREGATION | associated_with | phenotype | 0.45 |
| HIPPOCAMPUS | expressed_in | brain_region | 0.35 |
| CEREBRAL CORTEX | expressed_in | brain_region | 0.35 |
| ALPHA-SYNUCLEIN | activates | gene | 0.35 |
| AMYGDALA | causes | brain_region | 0.35 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning OLFACTORY BULB in their description or question text
No additional research found