protein

NMDA-RECEPTOR

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NMDA-RECEPTOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections

0Hypotheses

0Analyses

5Outgoing

3Incoming

0Experiments

0Debates

Summary

NMDA Receptor

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🔬 Protein Info

Gene Symbol	NMDA
Full Name	RECEPTOR
Aliases	GRIN2B, GRIN1
Molecular Weight	166 kDa
Pathways	glutamate signaling, unfolded protein response, oxidative stress response, mitochondrial function, sphingolipid metabolism
GeneCards	NMDA
Human Protein Atlas	NMDA
Associated Diseases	ALS, Alzheimer, Alzheimer'S Disease, disease, epilepsy, Huntington
Known Drugs/Compounds	memantine
Interactions	ABCA7, AMPA RECEPTOR, AMYLOID, APP, ATP, BAK
KG Connections	211 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

🔮 Predicted Structure: NMDA-RECEPTOR — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Pathway Diagram

flowchart TD
    NMDA_RECEPTOR(["NMDA-RECEPTOR"])
    NEUROTOXICITY("NEUROTOXICITY")
    ALZHEIMER(["ALZHEIMER"])
    Alzheimer_S_Disease["Alzheimer'S Disease"]
    disease["disease"]
    ALZHEIMER_S("ALZHEIMER'S")
    NMDA(["NMDA"])
    Neurodegeneration["Neurodegeneration"]

    NMDA_RECEPTOR -->|"protects against"| NEUROTOXICITY
    NMDA_RECEPTOR -->|"associated with"| ALZHEIMER
    NMDA_RECEPTOR -->|"associated with"| Alzheimer_S_Disease
    NMDA_RECEPTOR -->|"associated with"| disease
    NMDA_RECEPTOR -->|"associated with"| ALZHEIMER_S
    NMDA -->|"protects against"| NMDA_RECEPTOR
    NMDA -->|"associated with"| NMDA_RECEPTOR
    Neurodegeneration -->|"protects against"| NMDA_RECEPTOR

    style NMDA_RECEPTOR fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (5)

Target	Relation	Type	Str
ALZHEIMER	associated_with	gene	0.50
Alzheimer'S Disease	associated_with	disease	0.50
disease	associated_with	disease	0.50
ALZHEIMER'S	associated_with	concept	0.50
NEUROTOXICITY	decreases_risk	concept	0.50

Incoming (3)

Source	Relation	Type	Str
NMDA	associated_with	protein	0.50
NMDA	decreases_risk	protein	0.50
Neurodegeneration	decreases_risk	disease	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NMDA-RECEPTOR in their description or question text

No additional research found