gene

MT2A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MT2A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

13Connections

0Hypotheses

0Analyses

11Outgoing

2Incoming

0Experiments

0Debates

Summary

Metallothionein-2A metal homeostasis and neuroprotection

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🧬 Gene Info

Gene Symbol	MT2A
Full Name	Metallothionein-2A
Chromosome	16q13
Primary Expression	the brain and is upregulated in response to various cellular stresses
Molecular Weight	7 kDa
Amino Acids	61 aa
UniProt ID	P02795
NCBI Gene ID	4502
Ensembl ID	ENSG00000125148
OMIM	156361
GeneCards	MT2A
Human Protein Atlas	MT2A
Associated Diseases	Als
KG Connections	13 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: MT2A — AlphaFold P02795 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    MT2A["MT2A"]
    Tumor{"Tumor"}
    MT2A -->|"expressed in"| Tumor
    Senescence{"Senescence"}
    MT2A -->|"expressed in"| Senescence
    Als{"Als"}
    MT2A -->|"associated with"| Als
    Cancer{"Cancer"}
    MT2A -->|"expressed in"| Cancer
    Ataxia{"Ataxia"}
    MT2A -->|"expressed in"| Ataxia
    CANCER["CANCER"]
    MT2A -->|"expressed in"| CANCER
    APOPTOSIS["APOPTOSIS"]
    MT2A -->|"expressed in"| APOPTOSIS
    TERT["TERT"]
    MT2A -->|"expressed in"| TERT
    CFL1["CFL1"]
    MT2A -->|"associated with"| CFL1
    ATM["ATM"]
    MT2A -->|"expressed in"| ATM
    Apoptosis(["Apoptosis"])
    MT2A -->|"expressed in"| Apoptosis
    neurodegeneration["neurodegeneration"]
    MT2A -->|"implicated in"| neurodegeneration
    LGALS1["LGALS1"]
    LGALS1 -->|"associated with"| MT2A
    P4HB["P4HB"]
    P4HB -->|"associated with"| MT2A
    style MT2A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (11)

Target	Relation	Type	Str
Senescence	expressed_in	disease	0.65
Als	associated_with	disease	0.65
Cancer	expressed_in	disease	0.65
Ataxia	expressed_in	disease	0.65
Tumor	expressed_in	disease	0.65
TERT	expressed_in	gene	0.60
Apoptosis	expressed_in	pathway	0.60
CFL1	associated_with	gene	0.60
ATM	expressed_in	gene	0.60
CANCER	expressed_in	gene	0.60
APOPTOSIS	expressed_in	gene	0.60

Incoming (2)

Source	Relation	Type	Str
LGALS1	associated_with	gene	0.60
P4HB	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MT2A in their description or question text

No additional research found