concept

GAS5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GAS5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

25Connections

0Hypotheses

0Analyses

21Outgoing

4Incoming

0Experiments

0Debates

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💡 Concept Info

Name	GAS5
Key Genes/Proteins	BAX, BCL2, HIF1A, MALAT1, MMP2, MMP9
Related Diseases	colorectal cancer
Related Pathways	apoptosis pathway, autophagy pathway

Pathway Diagram

graph TD
    GAS5[GAS5]
    GAS5 -->|suppresses| colorectal_cancer[colorectal cancer]
    GAS5 -->|inhibits| cell_survival[cell survival]
    GAS5 -->|promotes| Apoptosis[Apoptosis]
    GAS5 -->|expressed in| NEAT1[NEAT1]
    GAS5 -->|activates| HIF1A[HIF1A]
    GAS5 -->|activates| MMP2[MMP2]
    GAS5 -->|activates| MMP9[MMP9]
    GAS5 -->|activates| VEGFA[VEGFA]
    GAS5 -->|activates| NLRP3[NLRP3]
    cardamom_nanoemulsion[cardamom nanoemulsion] -->|upregulates| GAS5
    BAX[BAX] -->|activates| GAS5
    BCL2[BCL2] -->|activates| GAS5
    benchmark_ot_ad_answer_key_GAS[benchmark_ot_ad_answer_key:GAS5] -->|data_in| GAS5

Outgoing (21)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:GAS5	data_in	dataset_row	0.00
colorectal cancer	suppresses	disease	0.85
Apoptosis	promotes	process	0.80
cell survival	inhibits	process	0.80
MALAT1	activates	gene	0.60
pyroptosis	participates_in	pathway	0.60
RNA	activates	gene	0.60
ubiquitin-proteasome	participates_in	pathway	0.60
oxidative stress response	participates_in	pathway	0.60
autophagy pathway	participates_in	pathway	0.60
NEAT1	expressed_in	gene	0.60
HIF1A	activates	gene	0.60
MMP2	activates	gene	0.60
MMP9	activates	gene	0.60
NEAT1	activates	gene	0.60
MALAT1	expressed_in	gene	0.60
VEGFA	activates	gene	0.60
apoptosis pathway	participates_in	pathway	0.60
NLRP3	activates	gene	0.60
ULK1	inhibits	gene	0.60
ULK1	activates	gene	0.60

Incoming (4)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:GAS5	data_in	dataset_row	0.00
cardamom nanoemulsion	upregulates	compound	0.85
BAX	activates	gene	0.60
BCL2	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GAS5 in their description or question text

No additional research found