| Gene Symbol | STMN2 |
| Chromosome | 8q21.13 |
| Function | Like other stathmin family members, it can sequester tubulin dimers, reducing the pool of free tubulin available for microtubule polymerization. |
| Primary Expression | Motor Neurons, Cortical Neurons, Sensory Neurons, Developing CNS |
| Subcellular Localization | STMN2 exhibits a distinctive subcellular distribution: |
| Molecular Weight | 20 kDa |
| Pathways | Axonal Regeneration |
| Ensembl ID | ENSG00000104435 |
| GeneCards | STMN2 |
| Human Protein Atlas | STMN2 |
| Growth cones | High concentration at distal axons during development |
| Synaptic terminals | Enriched in presynaptic compartments |
| Axon initial segment | Localized at the boundary between soma and axon |
| Membrane association | Via N-terminal myristoylation and polybasic region |
| Associated Diseases | ALS, frontotemporal dementia, neurodegeneration |
| Interactions | Actin, ALS, AMYOTROPHIC LATERAL SCLEROSIS, AND, ATP, AXON REGENERATION |
| SciDEX Hypotheses | STMN2 Restoration as a Prerequisite for Axon Growt |
| KG Connections | 119 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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