| Gene Symbol | STMN1 |
| Aliases | Stathmin 1 |
| Chromosome | 1p36.11 |
| Function | is a 143-amino acid phosphoprotein that serves as a master regulator of microtubule dynamics in all eukaryotic cells. |
| Molecular Weight | 19 kDa |
| Amino Acids | 149 aa |
| Exons | 5 |
| Pathways | MAPK |
| GeneCards | STMN1 |
| Human Protein Atlas | STMN1 |
| Ser16 | Phosphorylated by PKA and CaMKII, primary regulatory site |
| Ser25 | Phosphorylated by CDK1 and MAPK, cell cycle-dependent |
| Ser38 | Phosphorylated by multiple kinases including GSK3β |
| Ser63 | Major regulatory site, phosphorylated in response to various stimuli |
| Helical bundle (aa 80-120) | Primary tubulin-binding interface |
| Associated Diseases | Alzheimer's disease, Parkinson's disease, ALS |
| Interactions | CANCER, ERK, ERK1, ERK1/2, MEK |
| KG Connections | 40 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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