protein 1,005 words KG: SCD1PROTEIN
Contents

SCD1 Protein

🔬 Protein Info
Gene SymbolSCD1
AliasesSCD1PROTEIN
Chromosome10q24.31
Protein TypeEnzyme
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionmultiple cancers:
Subcellular Localization** | Endoplasmic Reticulum | [@hashimoto2020]
Molecular Weight60 kDa
Amino Acids360 aa
PathwaysAkt, Autophagy, Ferroptosis, Lipid Metabolism, Mtor
Ensembl IDENSG00000197294
GeneCardsSCD1
Human Protein AtlasSCD1
Six Transmembrane DomainsSpan the ER membrane in an alternating topology PMID: 18685521
Diiron CenterThe catalytic center contains a non-heme iron cofactor required for desaturation PMID: 19481183
Associated DiseasesALS, cancer, ferroptosis, Fibrosis
Known Drugs/CompoundsSalidroside
InteractionsACC, ACLY, ACSL4, AKT, ALOX15, AMPK
KG Connections260 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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