| Gene Symbol | NCL |
| Aliases | NUCLEOLIN |
| Protein Family | Nucleolin Family |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | proliferating cancer cells - Promotes angiogenesis via VEGF - Cell surface nucleolin targeted by anticancer drugs (e |
| Subcellular Localization | Nucleolus, Nucleus, Cytoplasm, Cell Surface |
| Molecular Weight | 76 kDa |
| Pathways | Apoptosis, Chromatin Remodeling, DNA Replication |
| UniProt ID | P19367 |
| GeneCards | NCL |
| Human Protein Atlas | NCL |
| N-terminal Domain | Acidic stretches (aspartate/glutamate-rich) for protein-protein interactions |
| Central Region | Contains four RNA recognition motifs (RRMs) |
| C-terminal Domain | Arginine-glycine-glycine (RGG) repeats for RNA binding |
| Nuclear Localization Signals (NLS) | Multiple NLS sequences |
| Associated Diseases | Alzheimer'S Disease, Autoimmune, cancer, disease, DISEASES |
| Interactions | Actin, AND, DNA, HNRNPA2B1, HNRPU, Proteins |
| KG Connections | 60 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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