protein 1,204 words KG: MECOMPROTEIN
Contents

MECOM Gene — MDS1 and EVI1 Complex

🔬 Protein Info
Gene SymbolMECOM
AliasesMECOMPROTEIN
Chromosome3q26
Protein TypeTranscription Factor
FunctionThe MECOM gene encodes a protein involved in various neurological processes.
Primary Expressionvarious brain regions including cortex, hippocampus, and cerebellum
Amino Acids725 aa
Exons16
PathwaysTGF-β signaling
UniProt IDQ03112
NCBI Gene ID2122
Ensembl IDENSG00000085276
GeneCardsMECOM
Human Protein AtlasMECOM
Associated Diseasesneurodegeneration
InteractionsAND, CANCER, EGFR, HDSP, HOXA10-HOXA9, SPINK1
KG Connections10 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (10)

Purinergic Signaling Polarization Control
Score: 0.71
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57

Related Analyses (10)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

Related Experiments (1)

Down Syndrome Alzheimer's Disease: Mechanisms and Therapeuti
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Alpha-Synuclein Seeding Assays (RT-QuIC and PMCA)
biomarker · Pages share 3 hypotheses
IL-6 (Interleukin-6) in Neurodegeneration
biomarker · Pages share 3 hypotheses
Cell-Free DNA Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses
Exosomal Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

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