protein 1,107 words KG: GABRB1PROTEIN
Contents

GABA-A Receptor Beta 1 Subunit

🔬 Protein Info
Gene SymbolGABA
Full NameA Receptor Beta 1 Subunit
Chromosome12p12.3
Protein FamilyCys-loop ligand-gated ion channel family
Functionis a hallmark of neurodegeneration.
Primary Expressionhippocampus, cortex, cerebellum, thalamus, hypothalamus
Amino Acids602 aa
Exons14
PathwaysGABAergic Signaling
UniProt IDP18505
NCBI Gene ID2565
OMIM137192
GeneCardsGABA
Human Protein AtlasGABA
Official SymbolGABRB1
Associated DiseasesAls, Alzheimer, Alzheimer's disease
Known Drugs/Compoundsrapamycin
InteractionsABCA7, ACTB, Actin, Akt, AKT, AKT1
KG Connections1369 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Related Hypotheses (6)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66

Related Analyses (9)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (3)

Metabolic Pathway-Targeted Therapy in ALS
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Non-Dopaminergic Neurotransmitter Degeneration in PD - Exper
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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