| Gene Symbol | GABA |
| Full Name | A Receptor Beta2 Protein |
| Chromosome | 12p12.3 |
| Function | is a hallmark of neurodegeneration. |
| Primary Expression | hippocampus, cortex, cerebellum, thalamus, hypothalamus |
| Subcellular Localization | </strong></td><td>Plasma membrane (synaptic)</td></tr> |
| Amino Acids | 602 aa |
| Exons | 14 |
| Pathways | GABAergic Signaling |
| GeneCards | GABA |
| Human Protein Atlas | GABA |
| Extracellular N-terminal domain | Contains the GABA binding site (at α-β interfaces) |
| Loop structures | 6 conserved loops (A-F) in the ligand-binding domain |
| Transmembrane domains | 4 helices (M1-M4) forming the ion channel |
| Intracellular loop | Between M3-M4, contains phosphorylation sites |
| Associated Diseases | Als, Alzheimer, Alzheimer's disease |
| Known Drugs/Compounds | rapamycin |
| Interactions | ABCA7, ACTB, Actin, Akt, AKT, AKT1 |
| KG Connections | 1369 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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