protein 887 words KG: FERROPORTIN
Contents

Ferroportin

🔬 Protein Info
Gene SymbolFERROPORTIN
Chromosome2q32.2
FunctionFerroportin serves as the cellular iron export channel
Subcellular LocalizationPlasma membrane, Endosomes
Molecular Weight70 kDa
Amino Acids571 aa
PathwaysAlpha-Synuclein, Ferroptosis
UniProt ID[Q9NP59](https://www.uniprot.org/uniprot/Q9NP59)
GeneCardsFERROPORTIN
Human Protein AtlasFERROPORTIN
Associated Diseasesneurodegeneration
InteractionsDJ-1, HEPCIDIN, TRANSFERRIN
KG Connections77 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (7)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Senescence-Induced Lipid Peroxidation Spreading
Score: 0.73
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Blood-Brain Barrier SPM Shuttle System
Score: 0.53

Related Analyses (9)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (3)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Ferroptosis Validation in Parkinson's Disease
clinical · proposed · Score: 0.40
Metal Ion Homeostasis Dysregulation in Alzheimer's Disease
validation · proposed · Score: 0.40

See Also (5)

DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: regulates
DMT1 Gene
gene · KG edge: associated_with
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: regulates
Alzheimer Indonesia
institution · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: regulates

Knowledge Graph (12 edges)

FERROPORTIN transports TFR1
FERROPORTIN transports DMT1
TFR1 regulates FERROPORTIN
FERROPORTIN regulates JUN
TFR1 transports FERROPORTIN
DMT1 transports FERROPORTIN
JUN regulates FERROPORTIN
DMT1 associated_with FERROPORTIN
FERROPORTIN associated_with TFR1
FERROPORTIN regulates Iron Metabolism

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