Contents

FANCC Protein

🔬 Protein Info

Gene Symbol	FANCC
Full Name	Fanconi Anemia Group C Protein
Chromosome	9q22.33
Protein Family	Fanconi anemia complementation group
Function	is a core component of the Fanconi anemia (FA) DNA repair pathway, a crucial mechanism for maintaining genomic stability through the repair of DNA interstrand crosslinks (ICLs) [1][2].
Primary Expression	Ubiquitous, high in bone marrow
Subcellular Localization	sites of DNA damage where they coordinate with specialized nucleases and helicases to remove crosslinks and restore geno
Molecular Weight	64 kDa
Amino Acids	558 aa
Pathways	pathway: [@pathway]
UniProt ID	Q00597
NCBI Gene ID	2176
Ensembl ID	ENSG00000144567
OMIM	603234
GeneCards	FANCC
Human Protein Atlas	FANCC
Associated Diseases	Alzheimer's disease, Parkinson's disease
Interactions	ATM, ATR, DNA, FANCA, FANCE, FANCI
KG Connections	26 knowledge graph edges
Databases	GeneCards HPA STRING

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