protein 648 words KG: CGASPROTEIN
Contents

cGAS Protein

🔬 Protein Info
Gene SymbolCGASPROTEIN
Target ClassEnzyme
Functionis an important component in the neurobiology of neurodegenerative diseases.
Mechanism of ActionSmall molecule inhibitor of cyclic dinucleotide synthesis
Subcellular Localization, post-translational modifications, and interaction with regulatory proteins
DruggabilityMedium (0.47)
Clinical StagePhase III
Molecular Weight57 kDa
GeneCardsCGASPROTEIN
Human Protein AtlasCGASPROTEIN
Associated Diseasesaging, Als, Alzheimer
Known Drugs/CompoundsAberrant DNA, cGAS Inhibitors, Ginkgetin, Mitochondrial Dna, Mitochondrial DNA, mtDNA
InteractionsACHE, Actin, AD, AGING, AHR, AKT
SciDEX TargetView Target Profile (4 clinical trials)
KG Connections1976 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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