| Gene Symbol | CARD14 |
| Aliases | CARD14PROTEIN |
| Chromosome | 2q31.1 |
| Function | is a gene encoding a member of the CARD family of that play critical roles in regulating cell death, inflammation, and immune signaling pathways[@jordan2012]. |
| Primary Expression | skin keratinocytes and immune cells, but also shows expression in various tissues including the brain[@chang2018] |
| Subcellular Localization | ** | Plasma membrane, endoplasmic reticulum | |
| Molecular Weight | 125 kDa |
| Pathways | NF-κB, NF-κB signaling |
| UniProt ID | Q9Y2K7 |
| NCBI Gene ID | 15292 |
| Ensembl ID | ENSG00000100916 |
| GeneCards | CARD14 |
| Human Protein Atlas | CARD14 |
| Coiled-coil domain | Mediates homomeric and heteromeric interactions with other CARD-containing proteins |
| CARD domain | Caspase recruitment domain for apoptotic and inflammatory signaling |
| Associated Diseases | neurodegeneration |
| Interactions | AND, BCL2, MITOPHAGY, MYC, NF-ΚB, PLIN4 |
| KG Connections | 20 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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