| Gene Symbol | BMAL1 |
| Full Name | Aryl Hydrocarbon Receptor Nuclear Translocator-Like |
| Chromosome | 11p15.3 |
| Protein Type | Transcription Factor |
| Target Class | Transcription Factor |
| Function | BMAL1 is a bHLH-PAS transcription factor with critical functions |
| Mechanism of Action | Small molecule modulator of circadian transcription |
| Subcellular Localization | </strong></td><td>Nucleus (primary)</td></tr> |
| Druggability | Low (0.34) |
| Clinical Stage | Phase I |
| Pathways | Akt, Apoptosis, Autophagy, CIRCADIAN_RHYTHM, Camp Signaling |
| UniProt ID | E9PL54 |
| NCBI Gene ID | 10518 |
| Ensembl ID | ENSG00000141510 |
| OMIM | 602550 |
| GeneCards | BMAL1 |
| Human Protein Atlas | BMAL1 |
| Associated Diseases | A2 phenotype, aging, Als, Alzheimer |
| Known Drugs/Compounds | lithium, nicotinamide, SXD |
| Interactions | Actin, adamts4, ADAMTS4, AGING, AHR, AKT |
| SciDEX Target | View Target Profile (2 clinical trials) |
| SciDEX Hypotheses | Circadian Rhythm Entrainment of Reactive Astrocyte |
| KG Connections | 1365 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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